Authors : Pratibha Bajpai, Seema Mishra, Sushma Ghai
Page Nos : 265-280
Description :
Hormone status is affected by environment, as proved by many previous studies. Stress is
now part of our environment. Mental Stress as Mental pollution has been drastically
increased in last decade. Now it is significantly affecting the in vivo hormonal production,
their chemistry and even their functioning. This stress as environmental pollutant
precipitates significantly low levels of progesterone, extremely high levels of testosterone,
hence Polycystic ovary syndrome..[PCOS] Between 1 in 10 women of childbearing age has
PCOS. It can occur in girls as young as 11 years,. Polycystic Ovary Syndrome, or PCOS, is a
metabolic disorder that affects the female reproductive system. The key characteristics in
the studied group include irregular menstruation, obesity, infertility, acne and hair growth
on the face, chest, and back (hirsutism ) and ovarian cysts. Some have Type 2 diabetes.
And most of them have effects of androgenic (masculinizing) hormones. Serum insulin
levels are significantly higher in subjects having PCOs, androgens, specifically testosterone,
and often less estrogen and progesterone than normal. Many other associated health
problems are also seen –dyslipidemia, autoimmune thyroiditis , high blood pressure. But
the most disastrous effect is stress via PCOs stimulates excessive production of Insulin,
finally Insulin Resistance Diabetes [ Type –II Diabetes ] is developed. Stress driven or PCOs
driven obesity is present in studied group. As High Testoesterone level is the single most
diagnostic criterion. Hyper insulinaemia is related to hyper androgonism. Body weight was
related to ovarian stroma and hirsutism. The study showed that stress has significantly
adverse effect on hormonal profile of the subjects and this condition is strongly co-related
with occurrence of PCOs and Diabetes in females.
Keywords: hormones, mental pollution, environmental pollutants
